|Assay:||NLT99%||Other Name:||3-Amino-4-phenylbutyric Acid Hydrochloride|
|Apprarence:||Crystal Powder||Usage:||Relieve Pain|
Antiepileptic Headache Relief Powder,
Pregabalin Headache Relief Powder,
Top quality Pregabalin Powder For Relieve Pain And Antiepileptic
1. Production Information Of Pregabalin
Pregabalin, chemical name (s) - 3-aminomethyl-5-methylhexanoic acid, molecular formula c8h17no2, is an antiepileptic drug, mainly for the treatment of postherpetic neuralgia.Pregabalin is an analogue of γ-aminobutyric acid (GABA), similar in structure and function to gabapentin, and has antiepileptic, analgesic and anxiolytic activities. The antiepileptic mechanism of pregabalin is still unclear. In laboratory studies, pregabalin has anticonvulsant activity on various epilepsy models; the activity spectrum of animal models is similar to that of gabapentin, but the activity of pregabalin is 3-10 times that of gabapentin.After oral administration, pregabalin takes effect within 30 minutes for acute toothache, lasting about 5 hours, and takes effect within 1 week for diabetic neuropathy. The peak time was about 1 h and the bioavailability was 90%. It is less metabolized in liver, 92% ～ 99% excreted by kidney in original form, less than 0.1% excreted by faeces in oral dose, with half-life of 5-6.5h
|Storage||stay in dry, cool and well-sealed|
|Package||1kg plastic drum|
Less on drying
|Heavy metals||10 ug/gMax|
|Loss On Drying||≤0.5%|
2. Funcation Of Pregabalin
As an anticonvulsant, pregabalin is mainly used for the treatment of adult partial epilepsy, diabetic neuralgia (pDPN), postherpetic neuralgia (PHN) and anxiety disorders. It is a GABA analogue that can bind to the central nervous system's voltage-dependent calcium channel α central subunit, and reduce neurotransmitters such as glutamate, norepinephrine, substance P, and calcitonin gene-related peptide freed.
1. Diabetic peripheral neuropathy neuralgia and postherpetic neuralgia .
2. Adjuvant treatment of partial seizures (foreign data) .
3. It can also be used for anxiety, social phobia and arthritis