Efficacy of Epithalon

Important Compliance Disclaimer

I. Core Action Pathways

1. Upregulate cellular telomerase activity to stabilize chromosomal telomere length and interfere with replicative cellular senescence;
2. Modulate pineal endocrine secretion, regulate melatonin synthesis, and balance genes related to oxidative stress and immunity.

II. Five Major Efficacies Observed in Laboratories

1. Activate telomerase and delay cellular senescence

    

   Slow down telomere shortening during continuous cell division and reduce the ratio of senescent and apoptotic cells. It is a core experimental material for aging and lifespan-related models.
2. Regulate endocrine and stabilize circadian rhythm

    

   Boost endogenous melatonin secretion in animal models and relieve circadian rhythm disorders, widely used in animal experiments on neuroendocrine and sleep mechanisms.
3. Powerful antioxidant effect and DNA protection against damage

    

   Scavenge intracellular ROS free radicals, alleviate DNA breaks induced by UV radiation and oxidative stimulation, and reduce oxidative aging damage of cells.
4. Immune regulation and research on tumor-related mechanisms

    

   Downregulate oncogene-related expression and reduce the incidence of spontaneous tumors in laboratory animals, applied to preclinical animal experiments on immune senescence and tumor prevention.
5. Protection of nerve and retinal cells

    

   Relieve oxidative damage of neurons and retinal pigment epithelial cells, commonly adopted in in vitro models of neurodegenerative diseases and ocular cell injury.

III. Applicable Research Scenarios (Laboratory Use Only)

1. Research on aging and lifespan mechanisms of cells and animals
2. Experiments related to pineal gland, endocrine and circadian rhythm
3. In vitro cell tests for anti-oxidation and DNA damage repair
4. Research on protection of retinal and nerve cells
5. Preclinical animal experiments related to inhibition of tumorigenesis