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Laxogenin (3beta-hydroxy-25D,5alpha-spirostan-6-one) is a compound sold in various forms as a muscle-toning supplement. It belongs to a class of plant hormones called brassinosteroids, which have a similar structure to animal steroid hormones. In plants, they work to boost growth.

The underground stems of the Asian plant Smilax sieboldii contain approximately 0.06% laxogenin and are its main natural source. Laxogenin is also obtained from Chinese onion (Allium chinense) bulbs.

Laxogenin in supplements is produced from the more common plant steroid, diosgenin. In fact, diosgenin is used as a raw material for over 50% of synthetic steroids including progesterone, cortisone.

Benefits

Effective alternative to prohormones.

Consider the types of muscle building supplement. If you disregard those that impact hormone levels such as prohormones, SARMS, testosterone boosters and estrogen blockers, the list of ingredients that can help users improve performance and recover faster become relatively limited. Laxogenin is one such ingredient.

Complements the use of protein supplements.

If you also disregard those supplements that are based around protein or protein breakdown products such as BCAAs, the list becomes shorter still. Laxogenin sits in this camp alongside other ingredients we will be reviewing in this series, such as epicatechin, arachidonic acid and creatine.

Fast-acting.

With Laxogenin supplements tending to kick in very quickly, they are ideal for anyone looking to build muscle and strength quickly.

Can be stacked with prohormones. Laxogenin can be stacked with other supplements such as testosterone boosters and estrogen blockers to amplify muscle building and recovery across two distinct pathways. This makes a lot more sense than the more common approach of stacking 2 or 3 different testosterone boosters that all target the exact same pathway.

Can be used for PCT (post cycle therapy).

This also makes Laxogenin products a wise choice following a prohormone cycle as they help promote anabolism via a different pathway to the likes of testosterone boosters.

Recommended Dosage for 5α-Hydroxy Laxogenin

5α-Hydroxy Laxogenin complements creatine, protein powder, branched chain amino acids and prohormones. This intense muscle training stack is intended for hardcore athletes trying to achieve extreme body shape and strength. So far, there is not enough evidence to prove the optimal dose of 5α-hydroxy Laxogenin. However, according to Russian animal research and some 5α-Hydroxy Laxogenin supplement products on the market, we recommend that the dosage of 5α-Hydroxy Laxogenin is 25-60mg per serving, two servings per day. And it should be taken within a 4-week or 8-week cycle to maximize the expected effect.